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China Daily / 2025-03 / 28 / Page004

Scientists leverage AI to design protein dataset

By Zhou Wenting in Shanghai | China Daily | Updated: 2025-03-28 00:00
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Scientists in Shanghai have made a breakthrough in protein design by leveraging artificial intelligence, establishing the world's largest protein sequence dataset and developing models that enable targeted modification and selection of proteins with specific functions.

The advancement has the potential to drastically reduce the time and cost involved in industrial protein modification, according to researchers from Shanghai Jiao Tong University.

Proteins play key roles in industries ranging from pharmaceuticals to green manufacturing. However, natural proteins often require modification to withstand environmental factors such as temperature shifts and acidity levels. For example, if a protein is used in laundry detergent, it must function in both hot and cold water to effectively break down stains.

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